Minimum inhibitory concentrations of penicillin and minocycline for 300 isolates of N. gonorrhoeae.
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Minimum inhibitory concentrations of penicillin and minocycline for 300 isolates of N. gonorrhoeae.
The minimum inhibitory concentrations of penicillin and minocycline were measured on 300 consecutive isolates of N. gonorrhoeae from patients attending the Nottingham treatment centre. 210 (70 per cent.) of these were fully sensitive to penicillin (MIC less than 0-1 mug./ml) and 89 per cent. were fully sensitive to minocycline (MIC less than 0-5 mug./ml.). Of the nine strains resistant to penic...
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Actinospectacin, a broad-spectrum antibiotic derived from Streptomyces spectabilis, was released for clinical trials more than 10 years ago. Although it possesses activity against many micro-organisms, both Gram-positive and Gram-negative, its use has been limited mainly to the treatment of gonorrhoea. Its efficacy in the treatment of this disease has been reported by a number of investigators....
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Production of staphylococcal beta-lactamase was shown to be correlated with penicillin G minimum inhibitory concentrations (MICs) of greater than 0.05 microgram/ml for 97% of the Staphylococcus aureus and 99% of the Staphylococcus epidermidis strains tested. However, it is important to note that of the isolates for which MICs were equal to or less than 0.05 micro/ml, a significant percentage (1...
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متن کاملDetermination of minimum inhibitory concentrations.
Minimum inhibitory concentrations (MICs) are defined as the lowest concentration of an antimicrobial that will inhibit the visible growth of a microorganism after overnight incubation, and minimum bactericidal concentrations (MBCs) as the lowest concentration of antimicrobial that will prevent the growth of an organism after subculture on to antibiotic-free media. MICs are used by diagnostic la...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1975
ISSN: 1368-4973
DOI: 10.1136/sti.51.4.265